Beneficial Effect of Alkaloids From Sophora alopecuroides L. on CUMS-Induced Depression Model Mice via Modulating Gut Microbiota
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چکیده
منابع مشابه
Sophora alopecuroides L. var. alopecuroides alleviates morphine withdrawal syndrome in mice: involvement of alkaloid fraction and matrine
OBJECTIVES Evaluation of the Sophora alopecuroides var. alopecuroides seed effects on morphine withdrawal syndrome in mice and determination of the alkaloid composition of the seed total extract. MATERIALS AND METHODS The effects of the seed total extract, alkaloid fraction and major compound matrine on the mice morphine withdrawal syndrome were compared to saline and methadone. Mice were mad...
متن کاملCharacterisation and antimicrobial activity of Sophora alopecuroides L. var. alopecuroides alkaloid extracts
Th e aerial parts and seeds of Sophora alopecuroides L. var. alopecuroides growing in Turkey were investigated for their alkaloid compositions and antimicrobial activities. Th e alkaloid extracts were analysed by capillary gas chromatography-mass spectrometry (GC-MS). Th e main components were identifi ed as sophoridine (33.07%), matrine (24.03%), and sophocarpine (8.01%) in the aerial parts, a...
متن کاملEffects of Total Alkaloids of Sophora alopecuroides on Biofilm Formation in Staphylococcus epidermidis
Staphylococcus epidermidis (S. epidermidis) is an opportunistic pathogen with low pathogenicity and a cause of the repeated outbreak of bovine mastitis in veterinary clinical settings. In this report, a biofilm model of S. epidermidis was generated and the minimal inhibitory concentration (MIC) and sub-MIC (SMIC) on bacterial cultures were assessed for the following agents: total alkaloids of S...
متن کاملMorphine withdrawal attenuating effect, toxicity and alkaloid composition of Sophora alopecuroides L. var. alopecuroides
Background and objectives: The seedsof Sophora alopecuroides L. var. alopecuroides may benefit treatment of opioid dependence. Therefore, the plant alkaloid composition, toxicity and effects on morphine withdrawal were studied. Methods: The alkaloid composition was determined by GC and GC/MS analysis. Mice were made dependent by morphine injec...
متن کاملSophora alopecuroides L. var. alopecuroides alleviates morphine withdrawal syndrome in mice: involvement of alkaloid fraction and matrine
Objective(s): Evaluation of the Sophora alopecuroides var. alopecuroides seed effects on morphine withdrawal syndrome in mice and determination of the alkaloid composition of the seed total extract. Materials and Methods:The effects of the seed total extract, alkaloid fraction and major compound matrine on the mice morphine withdrawal syndrome were compared to saline and methadone.Mice were ma...
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ژورنال
عنوان ژورنال: Frontiers in Cellular and Infection Microbiology
سال: 2021
ISSN: 2235-2988
DOI: 10.3389/fcimb.2021.665159